Time-Dependent Ventilatory Response to Poikilocapnic Hypoxia during Light and Dark Periods and the Role of Histamine H1 Receptors in Mice
J Physiol Sci Vol.58, No.2 pp.147-150
Abstract: We tested the hypothesis that the biphasic ventilatory response to poikilocapnic hypoxia shows circadian variation and contribution of histamine H1 receptors in mice. Initial increases in ventilation were augmented during dark periods. H1 receptors had no major relationship with circadian variation, but affected the declined phase.
Second Department of Physiology, Showa University School of Medicine, Shinagawa-ku, Tokyo, 142-8555 Japan. michiko@med.showa-u.ac.jp
Copyright© 2007 by The Physiological Society of Japan