Cytochalasin D as the Depressant of Contraction for the Optical Monitoring of Action Potentials in Isolated Rat Atrium
J Physiol Sci Vol.56, No.5 pp.385-388
Abstract: We used cytochalasin D to reduce contraction-related optical signals by inhibiting muscle contraction for the optical monitoring of action potentials, using a voltage-sensitive dye in isolated rat atrium preparations. The suppression of contraction-related signals was so strong that we concluded that this chemical is suitable for this purpose.
Department of Physiology, University of the Ryukyus School of Medicine, Okinawa, 903-0215, Japan. tsakai@med.u-ryukyu.ac.jp
Copyright© 2007 by The Physiological Society of Japan