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Responses of Acetylcholine Release and Regional Blood Flow in the Hippocampus during Walking in Aged Rats

J Physiol Sci Vol.56, No.3 pp.253-257
Sae Uchida, Atsuko Suzuki, Fusako Kagitani, Harumi Hotta
Abstract: Walking produced increases in both the extracellular acetylcholine level and regional blood flow in the hippocampus in aged rats 26–29 months old. The present results in aged rats were compared with our previous data in young adult rats (Nakajima et al., 2003), and it was found that both the acetylcholine and blood flow responses in the hippocampus were well maintained in aged rats.

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Department of the Autonomic Nervous System, Tokyo Metropolitan Institute of Gerontology, Itabashi-ku, Tokyo, 173-0015 Japan. suchida@tmig.or.jp