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Optical Mapping of Tachycardia-Like Excitation Evoked by Pacing in the Isolated Rat Atrium

Jpn J Physiol Vol.54, No.6 pp.593-599
Tetsuro Sakai
Abstract: Multiple-site optical recording of membrane potential activity using a voltage-sensitive dye was employed to monitor action potentials in the rat atrium. Electrical pacing at 1 Hz evoked the events of tachycardia-like excitation (TE). Optical mapping revealed that a coupling of spontaneous and evoked action potentials resulted in the initiation of TE.

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Department of Physiology, Tokyo Medical and Dental University Graduate School and Faculty of Medicine, Tokyo, 113-8519 Japan. tsakai@med.u-ryukyu.ac.jp