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A New Quantitative Filtration Apparatus to Evaluate Erythrocyte Deformability

Jpn J Physiol Vol.53, No.6 pp.481-486
Tetsuzi Koyama, Toru Maruyama, Ritsuko Seki, Edgar A. O'Rear, Hideo Shio, Nobuhiro Uyesaka
Abstract: We have developed a quantitative filtration apparatus to evaluate erythrocyte deformability, using a precision metal filter which we developed. The test material is sucked into the filter through the action of decreasing negative pressure. The device automatically gives a liquid level (height)–time relation and a pressure–flow rate relation, similar to gravity-based filtration. Unlike the gravity-based system, the experimental performance of this system is very good and reproducible.

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Tsukasa Sokken Co., Ltd., Setagaya-ku, Tokyo, 158-0087 Japan. uyesaka@nms.ac.jp